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Zista (Certirizine)

Written by Dr. Feargus McConnell, BVSc on the Jan.16, 2024

Petdirect is dedicated to providing educational pet health content for pet parents. This article was written and reviewed by veterinary professionals to answer common questions about your pet’s medication. Our focus is on delivering unbiased information to help you understand how medication works, its potential side effects, and FAQs for your reference. Always administer medication directly as prescribed by your vet. This article shouldn’t take the place of advice from your vet.

What is Zista?

Zista is a human antihistamine medication that veterinarians may prescribe off-label to pets. The active ingredient is Cetirizine. It is an antihistamine used to manage allergy signs in pets. It's primarily prescribed for allergic dermatitis and atopy (itchy skin) in dogs. It helps cats treat chronic rhinosinusitis (inflammation of nasal passage and sinuses) and itchy skin.

How does it work?

Allergies trigger the release of histamine in the body. Cetirizine works by blocking the effects of histamine on H1 receptors on cells in the body. By doing so, it reduces swelling, itchiness, and allergy symptoms.

Dose and Administration

Follow the instructions as prescribed by your vet. It is typically given once or twice a day to dogs and cats. The dose and frequency may requiring adjusting. Some pets respond better to Cetirizine than others. For pets that don’t responed alternative treatments may be required.

Overdose:

Although rare, overdose symptoms can include hyperactivity, vomiting, sleepiness, dilated pupils, increased heart rate and diarrhoea. In such cases, contact your vet or the National Poisons Centre at www.poisons.co.nz/animal-helpline/ or phone 0800 869 738.

Contraindications and Precautions

While Zista is generally safe, it should not be used in animals allergic to the drug. Zista is not recommended for animals with severe renal impairment. Caution is advised for animals at risk of urinary retention or convulsions.

Possible interactions with other medications, especially central nervous system depressants, should be discussed with your veterinarian.

Potential Side Effects

Common side effects of Zista can include:

  • Sedation
  • Lethargy
  • Vomiting
  • Drooling
  • Loss of appetite

If any of the above occur, contact your veterinarian immediately.

Storage

Zista should be stored as instructed by the label, however it is typically kept at room temperature, avoiding moisture and light. For safety keep out of reach of children and other pets.

Frequently Asked Questions (FAQ)

Is Zista safe for both cats and dogs?

  • Zista is generally considered safe however it should only ever be given to pets under veterinary guidance.

What are Zista common side effects in pets?

  • Sedation, lethargy, vomiting, drooling and loss of appetite. If you observe any of these, contact your veterinarian immediately.

Can Zista be given with food?

  • Yes, it can be administered with or without food.

How quickly does Zista start working in pets?

  • Typically, within 20 minutes to an hour after administration.

Conclusion

We hope this article provides a clear understanding of Zista for your pet. Remember, always seek advice from your veterinarian for any health-related decisions for your pets.