VetAce (Benazepril Hydrochloride)

VetACE is an oral tablet that contains Benazepril as the active ingredient. Benazepril is an angiotensin-converting enzyme (ACE) inhibitor. For dogs, VetACE is used for treating heart failure, often caused by issues with the heart's valves (mitral regurgitation) or a condition where the heart becomes enlarged (dilated cardiomyopathy). For cats, VetACE is used for chronic kidney disease and a heart condition called hypertrophic cardiomyopathy.

The active ingredient Benazepril functions by decreasing blood pressure and widening blood vessels, thus reducing the workload on the heart. It achieves this by blocking ACE, a protein that narrows blood vessels. This relaxation of blood vessels leads to decreased blood pressure. In pets with kidney disease, it helps in reducing protein leakage into the urine by relaxing the kidney's blood vessels which lowers their blood pressure.

It is important to follow the veterinarian’s directions regarding dosage and administration. Typically the usual dosage is once a day, ideally with or without food whilst avoiding high sodium treats. It is important to ensure your pet has constant access to water while on this medication.

Missed dose:

If a dose is missed please consult your veterinarian for guidance. They may advise to give the next dose as soon as you remember, unless it is close to the next dose, in which case skip the missed dose and give the next due dose as scheduled.

Overdose:

Symptoms of overdose can include signs of low blood pressure (hypotension) such as tiredness, dizziness, lethargy, changes in thirst and urination and incoordination. If any of these symptoms are present it is essential to contact your veterinarian or the New Zealand National Poisons Centre (0800 869 738 or www.poisons.co.nz/animal-helpline/) in case of suspected overdose.

VetAce has not been tested in pregnant or lactating animals so therefore it is recommended to discuss this with your veterinarian for what is best for your pet. It is important to discuss all medications your pet is currently taking as combining VetACE with other medications could lead to hypotensive effects.

While generally well-tolerated, the most common side effect is tiredness. Hypotension (low blood pressure) can occur and signs include tiredness or dizziness, or reluctance to get up. If this is observed or have any other concerns, contact your veterinarian.

It is important to follow the storage instructions. It is usually recommended to store VetACE at room temperature, in a tightly closed container, away from moisture and light. Keep out of reach of children and pets.

How long does it take for Benazepril to work in pets?

• Your veterinarian might suggest regular testing to monitor your pet’s response. However, it may start taking effect within 1-2 hours of administration, but visible improvements could take several days.

Is VetACE safe for all cats and dogs?  

• VetACE is generally safe but may not be suitable for pets with certain conditions. Your veterinarian will assess your pet's suitability for this medication.

Are there any dietary considerations while my pet is on VetAce (Benazepril)?

• Your veterinarian may recommend specific dietary modifications, particularly emphasising the avoidance of high-sodium foods. This recommendation aligns with the goal of maintaining optimal blood pressure levels, a critical aspect when administering medications like VetACE that are designed to lower or regulate blood pressure. Additionally, a low-sodium diet contributes to better heart health and reduces fluid retention. This effectively reduces the cardiac workload and overall supports your pets heart.