Trocoxil® (Mavacoxib)

Trocoxil® (Mavacoxib) is a medication commonly used for managing pain and inflammation in dogs with degenerative joint disease. Trocoxil is available in a range of chewable tablet strengths, including 30mg, 75mg, and 95mg. Your veterinarian will choose the appropriate concentration based on what is most suitable for your pet's needs.

Trocoxil® is a non-steroidal anti-inflammatory drug (NSAID) containing Mavacoxib as the active ingredient. Mavacoxib works by inhibiting cyclo-oxygenase pathway (COX), with a preference for COX-2. This action helps in reducing pain and inflammation.

Follow your veterinarian’s directions or the instructions on the drug label for dosage and administration. Give with food either immediately before or during the dog’s main meal.

Trocoxil is not a daily treatment. It is given monthly after two initial loading doses given 14 days apart. This regime is generally not advised to exceed seven consecutive doses (approximately 6.5 months). The tablet should be given as soon as it is removed from the blister pack.

Overdose:

Although Trocoxil® has a wide safety margin it is important to look out for signs that could indicate an overdose. Symptoms of an overdose may include loss of appetite, diarrhoea and vomiting.

If you suspect an overdose, or if a child may have accidentally eaten Trocoxil, contact your veterinarian or the New Zealand National Poisons Centre (www.poisons.co.nz/animal-helpline/ or 0800 869 738).

If your pet has previously demonstrated sensitivity to NSAIDs, it is generally advised to use Trocoxil with caution. It is also recommended to be cautious in conjunction with other NSAIDs or steroids. Special consideration is advised for dogs with pre-existing conditions such as cardiac, hepatic, or renal diseases, as well as those suffering from dehydration or bleeding disorders. Additionally, the safety of Trocoxil in pregnant, lactating, or breeding dogs has not yet been confirmed. While this information is intended to guide you, always prioritise the advice and directions of your veterinarian for your pet's specific healthcare needs.

Possible side effects of Trocoxil® can include vomiting and diarrhoea. In addition, more uncommon side effects that could occur include apathy (lack of interest) and loss of appetite and in very rare cases renal disorders. If observed, it is important to consult your veterinarian.

Store Trocoxil® at room temperature, away from light and moisture. It is important to keep the tablets away from children and other animals. It is vital to keep this medication away from children as accidental ingestion can lead to serious gastrointestinal upset.

Can Trocoxil® be used for cats?

• Trocoxil® is typically used in dogs. For options suitable for your cat, your vet can provide the best guidance and recommendations.

How long does it take for Trocoxil to start working?

• Trocoxil® typically reaches therapeutic levels within one hour of administration, but it's important to remember that every pet is different. Therefore, discussing the expected response time and effectiveness of Trocoxil® with your veterinarian is important.

Why is Trocoxil® only given once a month?

• A distinctive feature of Mavacoxib is its prolonged half-life in the body. This means it stays active and effective for a longer period compared to many other NSAIDs. Due to this extended duration of action, a monthly dose is usually sufficient to maintain therapeutic levels of the drug in the dog's system.