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Tricin (Polymyxin B Sulfate, Bacitracin Zinc, Neomycin Sulfate)

Written by Dr. Feargus McConnell, BVSc on the Jan.16, 2024

Petdirect is dedicated to providing educational pet health content for pet parents. This article was written and reviewed by veterinary professionals to answer common questions about your pet’s medication. Our focus is on delivering unbiased information to help you understand how medication works, its potential side effects, and FAQs for your reference. Always administer medication directly as prescribed by your vet. This article shouldn’t take the place of advice from your vet.

What is Tricin?

Tricin is a topical ointment, formulated with three key active components: Polymyxin B Sulphate, Bacitracin Zinc, and Neomycin Sulphate. This medicated ointment is primarily prescribed for treating bacterial infections affecting the eyes and ears. It is effective in addressing conditions such as conjunctivitis, superficial keratitis, and bacterial ear infections. It aids in reducing symptoms including soreness in the eyes, redness, swelling, discharge, crust formation on the eyelids, and ear-related symptoms such as scratching and rubbing.

How does it work?

  • Bacitracin Zinc: Effective against various Gram-positive bacteria and some Gram-negative cocci. It's resistant to destruction by Gram-negative bacteria, making it suitable for mixed infections.
  • Polymyxin B Sulphate: Targets numerous Gram-negative organisms effectively, with a low risk of bacterial resistance development.
  • Neomycin Sulphate: A broad-spectrum antibiotic, effective against both Gram-positive and Gram-negative organisms, and remains active in various conditions.

Dose and Administration

Before administering Tricin Eye and Ear ointment to your dog, ensure their ear/eye is clean and dry. Gently clear any debris or crust using a mild, non-irritating solution and trim any fur that may obstruct the treatment area.

Follow the directions provided by your veterinarian, but as a general guideline:

  • When applying the ointment to the eye, gently pull down the lower eyelid to create a small pocket and delicately dispense a small quantity of the ointment into this space.
  • For ear application, gently squeeze the amount prescribed into your pet's ear. Massage the ear carefully to spread the ointment thoroughly and ensure proper absorption.

The frequency and duration of applying Tricin Eye and Ear ointment are dependent on the condition being treated and your veterinarian's guidance. Frequency may vary from 4 to 12 times a day, or as frequently as treatment once per hour. Always wash your hands thoroughly before and after each application, and take care to avoid the tube's tip from coming into contact with the eye. Follow your veterinarian's advice closely, continuing the application for the recommended duration.

Missed Dose:

If you miss a dose, apply it as soon as possible unless it's almost time for the next dose. Do not double the dose.

Contraindications and Precautions

Avoid use if your pet:

  • Is allergic to any of the ingredients in Tricin.
  • Is pregnant or lactating.
  • Has a viral or fungal eye or ear infection.
  • Has a perforated eardrum.
  • Is taking a systemic aminoglycoside antibiotic.

Since Tricin is a form of antibiotic, antibiotic resistance is a potential risk in pets if used incorrectly. This resistance can make infections harder to treat. It's crucial to follow your vet's instructions for Tricin application strictly. Misuse, such as not applying enough or stopping treatment early, allows bacteria to adapt and become resistant. Proper use not only treats your pet's infection effectively but also helps in controlling antibiotic resistance.

Potential Side Effects

Side effects are uncommon but may include eye/skin irritation, such as stinging, itching, watery eyes, swelling, and redness. If these symptoms present it is important to contact your veterinarian immediately.

Storage

Follow the storage instructions as on the label. Typically it is advised to store in a cool dry place. It is important to not refrigerate this item.

Frequently Asked Questions (FAQ)

Can Tricin be used long-term?

  • Consult your vet for advice on treatment duration, as it varies based on the infection and treatment response.

Can Tricin be used for minor wounds?

  • Tricin is indicated for superficial eye and ear infections. Consult your vet for appropriate medication for wounds.

How quickly can I expect to see improvement in my pet’s condition after starting Tricin?

  • The time to see improvement in your pet's condition after starting Tricin varies depending on the severity and type of infection. Generally, some improvement may be noticeable within a few days of consistent treatment. However, it's crucial to complete the full course of treatment as prescribed by your veterinarian, even if symptoms appear to improve, to ensure the infection is fully resolved.

Can Tricin be used in conjunction with other medications?

  • Tricin may interact with other medications, so it's important to inform your veterinarian about all medications and supplements your pet is currently taking.

Can Tricin ointment be used preventatively for recurring infections?

  • Tricin is typically used to treat active infections and is not generally recommended as a preventive treatment. Continuous or repeated use without an active infection can lead to antibiotic resistance, making future infections harder to treat. For pets with recurring infections, it's best to discuss preventive strategies with your veterinarian.

What happens if Tricin is accidentally ingested by my pet?

  • If Tricin is accidentally ingested by your pet, it's important to contact your veterinarian or New Zealand National Poisons Centre (www.poisons.co.nz/animal-helpline/ or phone 0800 869 738). While the ointment is intended for topical use, ingestion could lead to potential complications, depending on the amount ingested and your pet's overall health.

Conclusion

Tricin is a specialised ointment for treating certain eye and ear infections in cats and dogs. Its effectiveness against a wide range of bacteria makes it a valuable option in veterinary care. Always consult your veterinarian for advice and follow their prescribed course of treatment to ensure the best outcomes for your pet.