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Tobradex (Tobramycin, Dexamethasone)

Written by Dr. Feargus McConnell, BVSc on the Jan.16, 2024

Petdirect is dedicated to providing educational pet health content for pet parents. This article was written and reviewed by veterinary professionals to answer common questions about your pet’s medication. Our focus is on delivering unbiased information to help you understand how medication works, its potential side effects, and FAQs for your reference. Always administer medication directly as prescribed by your vet. This article shouldn’t take the place of advice from your vet.

What is Tobradex?

The two active ingredients work together to combat bacterial infection and inflammation of the eye. Tobramycin belongs to the aminoglycoside class of antibiotics. It works by inhibiting bacterial protein synthesis. Dexamethasone is a corticosteroid, which is a type of anti-inflammatory agent. It works by suppressing the immune response, decreasing inflammation and alleviating pain, discomfort and swelling.

How does it work?

Tobramycin belongs to the aminoglycoside class of antibiotics. It works by inhibiting bacterial protein synthesis, which is essential for bacteria to grow and multiply. It's particularly effective against a variety of gram-negative and some gram-positive bacteria that commonly cause eye infections.

In contrast, Dexamethasone is a corticosteroid, which is a type of anti-inflammatory agent. It works by suppressing the immune response, particularly inflammation. Dexamethasone in the Tobradex formulation helps reduce the symptoms of inflammation, providing relief and preventing further damage to the eye tissues.

Dose and Administration

Follow your vet's instructions as the dosage and frequency can vary depending on the severity and type of condition being treated. However, here are some general guidelines for dosing and administering Tobradex to pets:

Wash Your Hands: Before and after administering the medication, wash your hands thoroughly to avoid contamination.

Prepare Your Pet: Calmly approach your pet and gently restrain them if necessary. It might be helpful to have someone assist you by holding your pet during the application.

Application Technique for Drops:

  • Gently clean the eye: If there is any discharge around your pet's eye, gently clean the area with a moist, soft cloth.
  • Hold the Bottle: Shake the bottle if instructed, then hold it using your thumb and index finger. Avoid touching the dropper tip to any surface, including the eye or hands, to keep it sterile.
  • Administer Drops: Use your other hand to gently pull down your pet’s lower eyelid to create a small pocket. Squeeze the prescribed number of drops into this pocket. Do not allow the dropper tip to touch the eye.

Application Technique for Ointment:

  • Gently Clean: Clean any discharge from around the eye.
  • Hold the Tube: Hold the ointment tube similar to the bottle, ensuring the tip doesn’t touch any surface, including the eye or hands.
  • Administer Ointment: Squeeze a small amount of ointment (as prescribed) onto the inside of the lower eyelid without touching the tube to the eye. A small strip of ointment is usually sufficient.

Completion:

  • Allow your pet to blink, as this helps to spread the medication evenly over the eye.
  • Praise and reward your pet to make the experience as positive as possible.

Contraindications and Precautions

Before treatment, the eye should be checked by a vet to rule out corneal ulceration. Tobradex should be avoided in cases of eye ulcers or infections caused by viruses or fungi.

Potential Side Effects

The most common side effects include mild allergic reactions. Symptoms of this can include:

  • Sensations of burning or stinging
  • Swelling or itching of the eyelids
  • Redness of the conjunctiva

Storage

Store at room temperature, away from moisture and sunlight, and do not freeze. Avoid using if the medication changes colour, becomes cloudy, or shows particles. For safety keep out of reach of children and other pets.

Frequently Asked Questions (FAQ)

How often should I apply Tobradex to my pet's eyes?

  • The frequency of Tobradex application can vary depending on the specific condition being treated and the severity of the infection or inflammation. Typically, your veterinarian will prescribe Tobradex to be applied several times daily.

What should I do if I miss a dose of Tobradex?

  • If you miss a dose of Tobradex, apply it as soon as you remember. However, if it's almost time for the next dose, skip the missed dose and proceed with the regular schedule. Do not double up on doses to make up for the missed one.

Can Tobradex cause side effects in my pet?

  • While Tobradex is generally safe for use in pets, as with any medication, there can be side effects. These may include increased eye watering, mild eye discomfort, redness, or a temporary blurring of vision after application.

How long will my pet need to use Tobradex?

  • The duration of treatment with Tobradex will depend on the condition being treated and how well your pet responds to the medication. Some conditions may require only a short course of treatment (a week or less), while others may need several weeks.

Conclusion

We hope this article provides a clear understanding of Tobradex for your pet. Remember, always seek advice from your veterinarian for any health-related decisions for your pets.