Written by Dr. Feargus McConnell, BVSc on the Jan.16, 2024
Petdirect is dedicated to providing educational pet health content for pet parents. This article was written and reviewed by veterinary professionals to answer common questions about your pet’s medication. Our focus is on delivering unbiased information to help you understand how medication works, its potential side effects, and FAQs for your reference. Always administer medication directly as prescribed by your vet. This article shouldn’t take the place of advice from your vet.
Simplicef (brand name) is a broad spectrum antibiotic containing Cefpodoxime as the primary ingredient. This medication is predominantly prescribed to treat various infections, particularly skin infections in dogs such as pyoderma, hot spots and wound infections. Though primarily used in dogs, veterinarians may sometimes prescribe ‘off-label’ for cats as well.
Classified as a third-generation cephalosporin, Cefpodoxime is effective against a broad range of bacteria. It functions by disrupting the production of bacterial cell walls, leading to the death of the bacteria. However, it's crucial to note that Cefpodoxime doesn't work against viruses, fungi, or parasites. Misuse can contribute to antibiotic resistance, so it's vital to use this medication strictly as directed by your veterinarian.
The dosage of Cefpodoxime is determined by your vet based on your pet's weight and infection type. It's usually given orally once daily and can be administered with or without food. To prevent digestive upset, giving it with a small meal might be beneficial. It's essential to follow the prescribed treatment course to ensure effectiveness.
Missed Dose:
If you miss a dose, consult your veterinarian. Avoid double dosing or making up for missed doses without veterinary advice.
Overdose:
Symptoms of overdose may include vomiting, diarrhoea, lethargy, and changes in appetite.
In case of a suspected overdose, seek emergency veterinary care immediately or contact the New Zealand National Poisons Centre at www.poisons.co.nz/animal-helpline/ or phone 0800 869 738.
Simplicef should not be given to dogs with a known allergy to cefpodoxime or the β-lactam group of antibiotics, which include penicillins and cephalosporins. It is not clear whether this medication is safe for gestating and lactating bitches or breeding male dogs. Like other cephalosporins, cefpodoxime proxetil may occasionally lead to a positive Coombs' test. It is important to note that β-lactam antibiotics, such as penicillins and cephalosporins, can cause sensitization following dermal or parenteral contact. In individuals who are already allergic, adverse reactions may occur. Therefore, people who are sensitised to this class of compounds should be aware of the risk of serious allergic reactions when handling the drug.
Cefpodoxime may cause potential side effects such as diarrhoea, vomiting, and decreased appetite. Allergic reactions, though rare, can occur. If you notice symptoms like skin rash, facial swelling, or trouble breathing in your pet, contact your veterinarian immediately.
Store Simplicef at controlled temperatures, whilst keeping it away from moisture and direct sunlight. Ensure it's out of reach of both children and pets.
Can Simplicef be used for both cats and dogs?
What should I do if I miss giving a dose to my pet?
Are there any specific side effects I should watch for?
Can human members of the household handle Simplicef?
We hope this article provides a clear understanding of Simplicef (Cefpodoxime) for your pet. Remember, always seek advice from your veterinarian for any health-related decisions for your pets.