Propalin (Phenylpropanolamine HCL)

Propalin® contains the active ingredient Phenylpropanolamine Hydrochloride which is most commonly used to treat urinary incontinence in dogs. It's important to note that it's not effective for incontinence caused by neurologic disease or malformations. Veterinarians may also prescribe it for cats, although this is considered an off-label use based at the vet's discretion and knowledge of the pet's specific needs.

Propalin® is classified as a sympathomimetic amine which mimics certain natural chemicals in the body. It aids in managing urinary incontinence by stimulating the smooth muscles in the urethra, bladder neck, and urethral sphincter, thereby improving muscle tone and closure of the bladder neck. Propalin® essentially aids your pet in maintaining better control over their urination.

Follow the dosage instructions provided by your vet or as stated on the Propalin® label. Typically, Propalin® can be given twice daily, using three drops of syrup per 4kg of the dog’s body weight, added to their food e.g. 15 drops for a 20kg dog, twice daily. An alternative dose can be given three times daily by adding one drop of syrup per 2kg of body weight to their food e.g. 10 drops for a 20kg dog, three times daily. Ensure your pet has access to plenty of water, as increased thirst can be a side effect.

Missed Doses:

If a dose is missed, consult your vet for advice. Generally, they may suggest administering it as soon as remembered but avoiding double dosing.

Overdose:

In case of a suspected overdose, immediately contact your veterinarian or the New Zealand National Poisons Centre at www.poisons.co.nz/animal-helpline/ or call 0800 869 738.

Propalin is not to be used in pregnant animals. It should not be used at the same time as other hypertensive medication (blood pressure medication).

While Propalin is generally well-tolerated and safe for dogs, side-effects can occur, and are more common at higher doses:

• Vomiting
• Diarrhoea
• Decreased appetite
• High blood pressure
• Weight loss
• Increased thirst
• Anxiety
• Abnormal heart rhythms
• Loss of appetite
• Restlessness and aggression
• Lethargy
• Musculoskeletal disorders

Consult your vet immediately if any of these side effects are observed.

Store Propalin® at a controlled room temperature, avoiding any extreme temperatures. Protection from any moisture and light is also recommended. Keep out of reach of pets and children.

Can Propalin® be used for both dogs and cats?

• Propalin® is primarily prescribed for dogs but may be used for cats on an off-label basis, only as prescribed by your vet. It is vital to discuss Propalin use with your vet before giving it to your cat.

Which pets can’t be prescribed Propalin®?

• Propalin is not for use in pregnant animals. Propalin is not for use in pet’s that are currently being treated with blood pressure medications (hypertensive drugs).

Are there any other considerations I should know about when using Propalin® for my dog?

• It's important to note that Propalin Syrup does contain sorbitol, a substance that can have a laxative effect. Keep this in mind as it may impact your dog's digestive system, however if you have any concerns or questions please contact your veterinarian.  

What if my pet is on other medications?

• Consult a veterinarian before combining Propalin with any other medication to ensure your pet's safety and health. Examples of drugs that are typically avoided when on Propalin® can include hypertension drugs, antidepressants and NSAIDs.