Written by Dr. Feargus McConnell, BVSc on the Jan.16, 2024
Petdirect is dedicated to providing educational pet health content for pet parents. This article was written and reviewed by veterinary professionals to answer common questions about your pet’s medication. Our focus is on delivering unbiased information to help you understand how medication works, its potential side effects, and FAQs for your reference. Always administer medication directly as prescribed by your vet. This article shouldn’t take the place of advice from your vet.
Pregabalin is a medication in the category of anticonvulsants. It is a human medication that may be prescribed off-label by vets for pets. It is primarily used for treating epilepsy in dogs. It is also used to treat neuropathic pain in pets. It may be prescribed as an add-on therapy in combination with other anti-seizure medication to aid in the management of epileptic dogs.
Pregabalin works by targeting a specific protein in nerve cells in the central nervous system. This binding influences the release of various neurotransmitters, including GABA and glutamate, which are involved in regulating pain and seizures. While the exact mechanisms and involvement of other neurotransmitters are still under investigation, this influence on neurotransmitters contributes to Pregabalin's effectiveness in managing these conditions. Adding Pregabalin to epileptic dogs not responding to phenobarbital may reduce seizure frequency by about 50%.
Always give Pregabalin as prescribed by your vet. Pregabalin is usually administered two to three times daily. The dose and frequency often require adjusting over time.
Missed Dose:
If you miss a dose, consult your veterinarian. They might suggest giving the missed dose as soon as you remember or skipping it if the next scheduled dose is near. Consult your veterinarian for any questions or concerns.
Overdose:
In cases of overdose, symptoms may include restlessness, agitation, and seizures. If you have suspicions of an overdose contact your veterinarian or the New Zealand National Poisons Centre can be contacted for guidance at www.poisons.co.nz/animal-helpline/ or phone 0800 869 738.
Pregabalin should not be given to pets with known hypersensitivity to it or its components.
Pets with liver or kidney disease may require dose adjustments.
Caution should be taken when using pregabalin in pregnant or lactating animals.
Use pregabalin with caution in pets with a history of drug sensitivities.
Pregabalin can enhance the effects of other CNS depressants, leading to increased sedation or respiratory depression.
Pregabalin can cause the following side effects:
If any of the above side effects occur, contact your veterinarian immediately.
Store Pregabalin at a controlled room temperature, avoiding direct sunlight and moisture. For safety keep out of reach from children and other pets.
Can Pregabalin be used for both cats and dogs?
How is Pregabalin administered?
Are there any long-term side effects of using Pregabalin in pets?
Can Pregabalin be used in conjunction with other medications?
We hope this article provides a clear understanding of Pregabalin for your pet. Remember, always seek advice from your veterinarian for any health-related decisions for your pets.