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Prednil (Prednisolone, Chlorpheniramine Maleate)

Written by Dr. Feargus McConnell, BVSc on the Jan.16, 2024

Petdirect is dedicated to providing educational pet health content for pet parents. This article was written and reviewed by veterinary professionals to answer common questions about your pet’s medication. Our focus is on delivering unbiased information to help you understand how medication works, its potential side effects, and FAQs for your reference. Always administer medication directly as prescribed by your vet. This article shouldn’t take the place of advice from your vet.

What is Prednil?

Prednil tablets are a veterinary medicine used to treat allergic reactions, dermatitis, and assist in managing arthritis and rheumatic joint diseases in cats and dogs. Each tablet contains Prednisolone and Chlorpheniramine Maleate. These ingredients work together to reduce inflammation and allergic reactions in pets. Prednisolone is a corticosteroid and Chlorpheniramine is an antihistamine.

How does it work?

Prednil tablets work through the combined actions of its two active ingredients. Prednisolone, as a corticosteroid, works by mimicking the effects of hormones in your pet's body. This action reduces inflammation, swelling, and pain. Chlorpheniramine blocks the action of histamine, a substance in the body that causes allergic symptoms.

Dose and Administration

The dose of Prednil varies depending on a variety of factors such as your pet’s body weight, the type of medical condition being treated, and the severity of the condition. It's important to follow the dosage instructions provided by your veterinarian closely.

Gradual Reduction in Dosage (Tapered Dose):

If your pet has been treated with Prednil tablets for a prolonged period, it's crucial to gradually reduce the treatment over time. This involves lowering the dose rates and frequency under the guidance of a veterinarian. Sudden withdrawal can lead to adverse effects due to suppression of the body's own hormone production.

Missed Dose:

If you miss a dose, administer it as soon as you remember. However, skip the missed dose if it's almost time for the next one. Do not double the dose.

Overdose:

In case of an overdose, contact your veterinarian or the New Zealand National Poisons Centre (www.poisons.co.nz/animal-helpline/ or 0800 869 738) immediately.

Contraindications and Precautions

Prednil should be administered cautiously in animals that have a history of hypersensitivity to corticosteroids or antihistamines. It is also crucial to inform your veterinarian of any other medications that your pet is taking as the drug may interact with them. If your pet has specific health conditions such as diabetes, heart disease, or kidney problems, careful monitoring or dosage adjustment may be necessary.

Potential Side Effects

While Prednil is generally well-tolerated by cats and dogs, it can cause a number of side effects. Side effects are more common with higher doses and prolonged use. Prednil might cause increased thirst, urination and appetite, panting, mild skin problems, and behavioural changes. However, it can also result in serious side effects such as gastrointestinal issues, muscle weakness, diabetes, liver and kidney problems, and a suppressed immune system. If you notice any adverse reactions in your pet, contact your veterinarian.

Storage

Prednil Tablets should be stored in a cool dry place below 25C, and kept out of reach of children.

Frequently Asked Questions (FAQ)

Can Prednil Tablets be used for any pet?

  • Prednil Tablets are specifically formulated for cats and dogs. They should not be used for other animals. Use directly as prescribed by your vet.

Are there any side effects of using Prednil Tablets?

  • As with any medication, Prednil Tablets can have side effects, although not every pet will experience them. Common side effects include drinking and urinating more, vomiting and diarrhoea, increased appetite, hyperactivity.

Can I stop giving my pet Prednil Tablets abruptly?

  • No, it's important to gradually reduce the dosage as directed by your veterinarian to avoid potential health risks.

How long should my pet be on Prednil Tablets?

  • The duration of treatment varies depending on the condition being treated and your pet's response to the medication. Always follow your veterinarian's guidance.

Conclusion

We hope this article provides a clear understanding of Prednil for your cat and dog. Remember, always seek advice from your veterinarian for any health-related decisions for your pets.