Polaramine (Dexchlorpheniramine)

Polaramin is a first-generation antihistamine containing the active ingredient Dexchlorpheniramine. It is a human medication that may be prescribed off-label by veterinarians for use in pets. Polarmine is used in pets primarily as an antihistamine to treat allergic reactions, such as those caused by insect bites, food allergies, or environmental allergens. It helps alleviate symptoms like itching, swelling, and redness.

Allergic reactions occur when allergens bind to antibodies present in immune cells called mast cells and basophils, causing the release of histamine. Histamine interacts with different tissues through histamine receptors. Dexchlorpheniramine is an active ingredient that functions as a histamine H1 antagonist. It competes with histamine for H1-receptor sites found in the gastrointestinal tract, respiratory tract and blood vessels. This helps relieve clinical signs commonly associated with allergies, like itchy skin.

The dosage and administration of Polaramine should be determined by a veterinarian based on the pets individual needs, including weight, health condition, and the severity of allergies. Polaramine comes in tablet form and is administered orally. Veterinarians will determine the appropriate dosage and frequency based on your dog's specific situation.

Overdose:

In the event of an accidental overdose, immediate veterinary assistance is necessary. For additional guidance, contact the New Zealand National Poisons Centre at www.poisons.co.nz/animal-helpline/ or phone 0800 869 738.

Avoid using Polaramine alongside other medications unless advised by a veterinarian due to potential interactions.

Be cautious in dogs with known allergies to any components of the medication.

Special consideration is required for pregnant dogs, as Polaramine can affect the foetus.

While Polaramine is generally safe when prescribed by a veterinarian, it can cause side effects. Common side effects include drowsiness, upset stomach, and dry mouth. Variability in symptoms is possible, and any concerning changes should prompt immediate consultation with a veterinarian.

Store at room temperature below 25 degrees. Keep out of reach of children and pets.

What should I do in case of an overdose?

• In the event of an overdose, it is important to seek immediate veterinary attention. For guidance, you can contact the New Zealand National Poisons Centre at www.poisons.co.nz/animal-helpline/ or phone 0800 869 738 for advice.

Can Polaramine be used for conditions other than allergies?

• This medication is primarily used for treating allergic conditions. It's essential to use it only for the purposes prescribed by a veterinarian.

Is Polaramine safe for all cats and dogs?

• Safety can vary depending on the individual health conditions of each pet. Always consult with a veterinarian before administering any new medication.