PMP Ear Suspension (Polymyxin B Sulphate, Miconazole Nitrate, Prednisolone Acetate)

PMP Ear Suspension is formulated to combat ear and skin infections in cats and dogs, particularly those caused by fungi, yeasts, and bacteria. The medication contains three active ingredients: Polymyxin B Sulphate, an antibiotic targeting Gram-negative bacteria; Miconazole Nitrate, a broad-spectrum antifungal effective against Gram-positive bacteria; and Prednisolone Acetate, a corticosteroid alleviating discomfort, itching, and preventing self-trauma from over-scratching.

• Miconazole Nitrate: This acts by interfering with fungal cell membrane function and has good antifungal activity. It's effective against most fungi, yeasts, and Gram-positive bacteria.
• Polymyxin B Sulphate: An antibiotic, is effective against Gram-negative bacteria. It disrupts bacterial cell membrane permeability, causing bacterial death.
• Prednisolone Acetate: This corticosteroid reduces inflammation to provide relief from itching and discomfort.

The dosage should be consulted with your veterinarian as it will vary depending on the condition. The following is as a guide only and shouldn’t replace instructions from your vet:

• For ear infections: 3-5 drops into the ear twice daily.
• For ear infections caused by ear mites: 5 drops twice daily for 2 weeks.
• For skin infections: Apply to the affected area, continuing treatment for several days after symptoms resolve.

It is advised to discuss with your veterinarian if this medication is suitable. However it is typically avoided in animals with hypersensitivity to the ingredients, tympanic membrane perforation (ear drum), known microbial resistance to the ingredients, or on lactating animals' mammary glands.

It is important to verify tympanic membrane (ear drum) integrity before treatment. This product should not be used if the eardrum is perforated.

PMP ear drops must not be used in dogs with perforated or damaged ear drums. In rare cases, deafness (especially in older dogs) can occur. While PMP ear drops are generally well-tolerated and safe, it's vital to contact your vet immediately if you notice any of the following side effects: head tilt, walking in circles, sudden hearing loss, worsening of ear pain. Other side effect might include loss of appetite, vomiting, diarrhoea, increased drinking and urination.

Your pet might have some redness or mild discomfort at the application site. Contact your vet if the infection is not improving or is getting worse even with treatment.

Prolonged use may lead to local immunosuppression, thinning of the skin, delayed wound healing, and systemic effects like adrenal suppression. If the following symptoms occur, contact your veterinarian immediately.

Store at room temperature, away from light. Keep out of reach of children and other pets.

What is PMP Ear Suspension used for?

• PMP Ear Suspension treats ear infections in cats and dogs. It is also licensed to treat skin infections and ear mites in dogs and cats.

Can this medication be used for any animal?

• It's specifically formulated for cats and dogs.

What should I do in case of an overdose?

• Contact your vet or the New Zealand National Poisons Centre immediately.

Are there any known side effects?

• While generally safe to use, it's vital to contact your vet immediately if you notice any of the following side effects: head tilt, walking in circles, sudden hearing loss, worsening of ear pain. Other side effects might include loss of appetite, vomiting, diarrhoea, increased drinking and urination. Contact your vet if the infection is not getting better, or is getting worse.