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Neurontin (Gabapentin)

Written by Dr. Feargus McConnell, BVSc on the Jan.16, 2024

Petdirect is dedicated to providing educational pet health content for pet parents. This article was written and reviewed by veterinary professionals to answer common questions about your pet’s medication. Our focus is on delivering unbiased information to help you understand how medication works, its potential side effects, and FAQs for your reference. Always administer medication directly as prescribed by your vet. This article shouldn’t take the place of advice from your vet.

What is Neurontin?

Neurontin contains Gabapentin as the active ingredient which is primarily used for pain relief, anti-seizure and anti-anxiety. Neurontin can be used alongside other medications to manage seizures, and is also effective in treating pain and chronic pain, such nerve-pain. Gabapentin can be used to reduce fear and anxiety associated with trips to the vet.

How does it work?

Neurontin’s exact mechanism of action is not fully understood. It is similar in structure to the neurotransmitter GABA and is thought to reduce the activity of certain neurotransmitters involved in pain, anxiety, and seizures. This can help in managing conditions where pets experience heightened sensitivity to pain or frequent seizures.

Dose and Administration

Follow instructions as prescribed by your veterinarian. It is important to never discontinue gabapentin abruptly, especially in pets with seizure disorders, as this may lead to withdrawal seizures. This is an oral medication which can be given with or without food. Dosage will depend on your pet's condition, consult your veterinarian.  

Missed Dose:

If you miss a dose, consult your veterinarian for advice. Generally, they may recommend administering the dose as soon as remembered or skipping it if it's close to the next scheduled dose.

Overdose:

Overdosing on Neurontin can result in symptoms such as lack of coordination, lethargy, vomiting, and diarrhoea. Seek immediate veterinary assistance if an overdose is suspected or contact New Zealand National Poisons Centre (www.poisons.co.nz/animal-helpline/ or phone 0800 869 738) immediately.

Contraindications and Precautions

Use with caution in pets with kidney problems, pregnant or lactating pets. Use with care in elderly pets as they may be more sensitive to the effects of gabapentin and require lower doses.

Consult your veterinarian for all drugs your pet is on to ensure they are safe to be used together. However, as a guide the following medications should be used with caution when given with gabapentin-based drugs: antacids, hydrocodone, or morphine.

Potential Side Effects

Common side effects in pets may include:

  • Sedation or drowsiness
  • Loss of coordination (ataxia)
  • Increased drooling and vomiting in cats

If you notice any adverse effects, consult your veterinarian immediately.

Storage

Store gabapentin at a controlled room temperature, ensuring the medication is in a tightly closed container to protect it from moisture and light. Keep out of reach from children and other pets.

Frequently Asked Questions (FAQ)

Can Neurontin be used for both cats and dogs?

  • Yes, Neurontin can be prescribed for both cats and dogs, but only under the guidance of a veterinarian.

Is Neurontin a veterinary-approved medication?

  • Neurontin is not specifically approved for veterinary use but is commonly prescribed in an off-label capacity for pets.

Can Neurontin be stopped abruptly?

  • No, it’s important to follow your veterinarian's instructions for discontinuing Neurontin, especially in pets being treated for seizures.

Is it safe to use human gabapentin formulations for my pet?

  • You should only use the formulation of gabapentin specifically prescribed by your veterinarian, as some human versions contain ingredients that are harmful to pets.

Conclusion

Neurontin (Gabapentin) is a common “off-label” prescribed medication in cats and dogs. However, it's crucial to follow your veterinarian's advice regarding its use. We hope this article provides a clear understanding of Neurontin for your pet. Remember, always seek advice from your veterinarian for any health-related decisions for your pets.