Written by Dr. Feargus McConnell, BVSc on the Jan.16, 2024
Petdirect is dedicated to providing educational pet health content for pet parents. This article was written and reviewed by veterinary professionals to answer common questions about your pet’s medication. Our focus is on delivering unbiased information to help you understand how medication works, its potential side effects, and FAQs for your reference. Always administer medication directly as prescribed by your vet. This article shouldn’t take the place of advice from your vet.
Cyclosporine is the main active ingredient found in Neoral. This medication is an immunosuppressant used specifically for controlling atopic dermatitis in dogs. Atopic dermatitis is a chronic inflammatory skin condition often caused by an allergic reaction. This condition can lead to intense itching, redness, and discomfort. It is administered in capsule form and is available in various strengths, including 25mg, 50mg, and 100mg capsules.
Cyclosporine, the active ingredient in Neoral, inhibits the activity of immune cells responsible for causing inflammation and allergic reactions in the skin and body. By suppressing these overactive immune responses, Neoral helps reduce inflammation, itching, and the overactive immune system responsible for immune-mediated diseases.
Your veterinarian will provide specific instructions for treating your pet with Neoral.
The dose and length of treatment depends on several factors, including the nature and severity of the health issue being treated. Gradual improvements are usually noticeable throughout the treatment, but it may take up to six weeks before the medication shows full effects, depending on the condition being treated.
Missed Dose:
If a dose is missed, administer it as soon as possible, but avoid doubling the dose. Consult your veterinarian if you have any questions.
Overdose:
Contact your veterinarian or the New Zealand National Poisons Centre at www.poisons.co.nz/animal-helpline/ or 0800 869 738.
Known Hypersensitivity: Animals with a known hypersensitivity to cyclosporine should not receive the medication.
Renal Dysfunction: Cyclosporine can be nephrotoxic, so it should be used with caution or avoided in animals with renal impairment.
Infections: Since cyclosporine suppresses the immune system, it should be used with caution in animals with active or chronic infections.
Cancer: Avoid use in animals with a history of certain cancers, as cyclosporine can potentially exacerbate cancer conditions.
Liver Disease: Caution is advised in patients with liver disease due to altered drug metabolism and excretion.
Pregnancy and Nursing: Cyclosporine should be avoided in pregnant or nursing animals, as its safety in these populations has not been well established.
The most common side effects of cyclosporine in dogs and cats are vomiting, diarrhoea, and decreased appetite.
Other possible side effects in dogs include urinary tract infections, lethargy, overgrowth of the gums, and enlarged lymph nodes.
Other side effects in cats include lethargy, drooling, conjunctivitis, sneezing, inflammation of the gums, increased hair growth, and increased drinking.
Cyclosporine suppresses the immune system and can increase the risk of infections developing.
Store Neoral in its original packaging at a controlled room temperature. Keep out of reach from children and other pets,
What is cyclosporine used for in dogs and cats?
How long does it take for cyclosporine to work?
Are there any side effects of cyclosporine in pets?
Can cyclosporine be used with other medications?
Is monitoring required during cyclosporine therapy?
Neoral (Cyclosporin) is a useful medication in managing auto-immune disease and atopic dermatitis in pets. While it offers benefits, understanding its usage, dosage, side effects, and precautions is important for responsible pet care. We hope this article provides a clear understanding of Neoral for your pet. Remember, always seek advice from your veterinarian for any health-related decisions for your pets.