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NeoMercazole (Carbimazole)

Written by Dr. Feargus McConnell, BVSc on the Jan.16, 2024

Petdirect is dedicated to providing educational pet health content for pet parents. This article was written and reviewed by veterinary professionals to answer common questions about your pet’s medication. Our focus is on delivering unbiased information to help you understand how medication works, its potential side effects, and FAQs for your reference. Always administer medication directly as prescribed by your vet. This article shouldn’t take the place of advice from your vet.

What is NeoMercazole?

NeoMercazole is used to treat hyperthyroidism in cats. It contains Carbimazole as the active ingredient. It is a human prescription medication that may be prescribed off-label by a veterinarian for cats. Hyperthyroidism in cats is a medical condition where the thyroid gland produces an excessive amount of thyroid hormone, leading to various health issues.

How does it work?

The active ingredient Carbimazole reduces the production of thyroid hormones in the thyroid gland. It inhibits the synthesis of these hormones by preventing the incorporation of iodine into the hormones thyroxine (T4) and tri-iodothyronine (T3), which are the primary thyroid hormones.

Dose and Administration

Give as directed by your vet. Typically, one tablet should be given orally and simultaneously each day, preferably in relation to feeding times. Absorption is increased with food. Tablets may be given with or without food as long as this is consistent daily. It is important not to break or crush the tablets as this can interfere with their efficacy. It is important to work closely with your veterinarian as dosage adjustments should be based on the cat's clinical assessment and monitored thyroid levels typically every 3 to 6 months.

Administering medication to cats, including NeoMercazole, can be challenging due to their nature and sometimes uncooperative behaviour. Here are some tips for giving tablets to cats:

  • Masking the Pill: Many cats will refuse to take a pill if they know it's there. You can hide the pill in a small amount of their favourite food or a special treat. There are also commercial pill pockets designed to hide medication.
  • Pill Popper (a.k.a. Pet Piller, Pill Shooter): This tool can help you place the pill directly at the back of the cat's mouth, beyond where they can easily spit it out.
  • Positive Reinforcement: After giving the medication, immediately reward your cat with a treat and affection. This can help make the experience more positive for your cat.
  • Helping hands: Pilling cats is often easier if one person holds the cat while the other administers the medication.

Overdose:

In case of a suspected overdose contact your veterinarian immediately or the New Zealand National Poisons Centre immediately (http://www.poisons.co.nz/animal-helpline/) or phone: 0800 869 738).

Contraindications and Precautions

As a guide, NeoMercazole is not typically recommended for cats with certain blood disorders, coagulopathies, pregnant or lactating animals. It is important to consult with your veterinarian for advice before starting this medication as it may not be a safe option for every animal.

Potential Side Effects

Common reactions can include vomiting, diarrhoea, reduced appetite, lethargy, skin issues, and changes in blood parameters. If you observe any of those symptoms, contact your veterinarian immediately. Regular monitoring and veterinary care are highly recommended to manage these side effects.

Storage

Store NeoMercazole at room temperature, away from moisture and light.

Frequently Asked Questions (FAQ)

Can NeoMercazole be used for dogs?

  • This medication is designed primarily for managing hyperthyroidism in cats and is generally not advised for use in dogs. For treatments related to dogs, it's essential to seek advice from your veterinarian regarding appropriate medications.

What are the signs of hyperthyroidism in cats?

  • Common signs include increased appetite, weight loss, hyperactivity, changes in coat condition, and sometimes aggression.

Does NeoMercazole cure hyperthyroidism?

  • NeoMercazole doesn't cure hyperthyroidism but helps manage the condition by regulating thyroid hormone levels.

Conclusion

NeoMercazole (Carbimazole) can be an effective medication for managing hyperthyroidism in cats. However, like all medications, it should be used under the guidance of a veterinarian to ensure the safety and health of your pet. Regular monitoring and adhering to prescribed dosages are important for the well-being of your pet.