Metoclopramide (Metoclopramide)

Metoclopramide is a prescription medication used to treat nausea and vomiting in dogs and cats. It is a human medication that may be prescribed off-label by a veterinarian for dogs and cats. It may also be used to stimulate stomach muscles to prevent esophageal reflux.

Metoclopramide acts on the brain to reduce the sensation of nausea. It also acts on the gut to help food move through the intestines. This helps prevent reflux and ensures the smooth passage of food through the intestines.

Give as directed by your veterinarian. It is often advised to give Metoclopramide on an empty stomach 20 minutes before food.

Missed Dose:

If a dose is missed, typically, you may be advised to administer the dose as soon as remembered or skip it if the next scheduled dose is near.

Overdose:

Contact your veterinarian immediately or the New Zealand National Poisons Centre (www.poisons.co.nz/animal-helpline/ or phone 0800 869 738).

The use of metoclopramide should be avoided in the following situations:

• Known hypersensitivity to metoclopramide.
• Gastrointestinal obstruction, perforation, or hemorrhage: Since metoclopramide stimulates motility, its use could be harmful in these conditions.
• Seizure disorders: Metoclopramide can lower the seizure threshold.

Use caution in animals with:

• Heart failure or other conditions where fluid retention is a concern, as metoclopramide can cause fluid retention.
• Renal or hepatic impairment: Dose adjustments may be necessary, as these conditions can affect the drug's metabolism and excretion.

Metoclopramide is generally well-tolerated and considered safe. Side effects are rare with metoclopramide. Pets that are affected by epilepsy may experience increased seizures, although this should not be a problem for normal animals. Some animals may experience drowsiness, and others may experience hyperactivity. Constipation has been reported in some individuals, but it is not a common side effect.

Store Metoclopramide at controlled room temperatures, in a cool, dry, dark place. Keep out of reach of children and pets.

Can Metoclopramide be used for both cats and dogs?

• Yes, it is commonly prescribed for gastrointestinal issues in both cats and dogs.

How often should I give Metoclopramide to my pet?

• The dosing schedule will be determined by your veterinarian based on your pet's specific needs.

Are there any serious side effects I should watch for?

• Metoclopramide is generally safe, with rare side effects. Epileptic pets may have more seizures. Drowsiness, hyperactivity, and constipation are possible side effects.

Is it safe to store Metoclopramide at home?

• Yes, store it at controlled room temperatures (20-25°C) and away from moisture and light.