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Methimazole Spot On MSO (Methimazole)

Written by Dr. Feargus McConnell, BVSc on the Jan.16, 2024

Petdirect is dedicated to providing educational pet health content for pet parents. This article was written and reviewed by veterinary professionals to answer common questions about your pet’s medication. Our focus is on delivering unbiased information to help you understand how medication works, its potential side effects, and FAQs for your reference. Always administer medication directly as prescribed by your vet. This article shouldn’t take the place of advice from your vet.

What is Methimazole Spot-on?

Methimazole Spot-on (Methimazole) is a medication commonly used to treat hyperthyroidism in cats. Hyperthyroidism in cats is usually the result of a benign change in one or both of the thyroid glands. This results in an overproduction of thyroid hormone and affects the cat’s metabolism. Common signs of hyperthyroidism can include weight loss despite increased appetite, increased vocalisation, increased drinking and urination, vomiting. The coat of affected cats may appear unkempt or greasy. Cats with hyperthyroidism can appear hyperactive, irritable and at times aggressive.

How does it work?

Methimazole works by inhibiting the use of iodine by the thyroid gland, essentially decreasing the thyroid gland’s ability to produce thyroid hormones. It's important to note that methimazole is not a cure but helps manage the symptoms by controlling hormone production.

Dose and Administration

Methimazole Spot-On is a gel formulation applied to the inside of the cat's ear and the dose should be tailored to your pet's individual needs and used strictly according to your veterinarian's prescription. Using a glove, or the finger cot supplied in the packaging apply the dose to the inside of the pinna of the ear . This medication is typically applied once daily.

Missed dose:

In case you miss a dose, administer it as soon as you remember. However, if it's almost time for the next dose, it is advised to wait until the next dose is due. Do not give two doses at the same time for your pet's safety.

Overdose:

In case of overdose, contact your veterinarian or the New Zealand National Poisons Centre at www.poisons.co.nz/animal-helpline/ or 0800 869 738.

Contraindications and Precautions

Methimazole should be used cautiously in pets with liver disease, autoimmune diseases, kidney disease, or blood abnormalities.

Potential Side Effects

Side effects most common within the first three months may include a lack of appetite, vomiting, diarrhoea, and depression.

Rare side effects can include severe itching, blood disorders and bleeding, liver disease, and immune disorders. Treatment may reveal pre existing underlying kidney disease. It is vital to contact your veterinarian immediately if you notice these side effects.

Storage and Handling

Methimazole Spot-on should be stored at controlled room temperatures below 25°C, avoiding extreme heat. Ensure the container is tightly sealed to protect from moisture and light. Keep out of reach of children and pets.

It is important to apply using a glove or the finger cot to protect yourself from absorbing this medication across your skin. Wash your hands well after administering this medication to your cat.

Cat owners with low thyroid function, bleeding disorders, or liver dysfunction should use extreme care when handling this medication. After a cat has been administered this medication, young children should wait one hour before playing with the cat to avoid accidental exposure to the drug before it is absorbed through the cat’s skin.

Monitoring

Regular routine testing and monitoring of thyroid levels and blood and urine testing is typically recommended for cats being treated with Methimazole. Initial testing can be done before starting treatment, followed by checkups and regular monitoring recommended by your vet. Adjustments in dosage might be necessary based on test results.

Frequently Asked Questions (FAQ)

How long does Methimazole Spot-on take to work on cats?

  • The effectiveness of methimazole can vary among individual pets and is best to consult with your veterinarian to discuss your individual expectations. Typically, improvements in your cat may be observed within 1-3 weeks.

How do I apply Methimazole Spot-On correctly?

  • It is important to follow the instructions set by your veterinarian. The starting dose is usually 0.1mL, applied once daily, to the skin on the inside of the pinna of the ear. It is important to administer at the same time each day. It is important to apply using a glove or the finger cot to protect yourself from absorbing this medication across your skin. Wash your hands well after administering this medication to your cat.

How long will my cat be on Methimazole Spot-on for?

  • The duration is typically a long-term commitment as this medication manages the symptoms rather than curing the underlying condition. The specific length of treatment can vary depending on the cat's response to the medication. It is essential to work closely with your veterinarian to regularly assess your cat's condition and adjust the treatment plan as needed. Other treatment options for hyperthyroidism include surgery, diet, and radioactive iodine.

Conclusion

Methimazole Spot-on treatment is a common medication for managing Hyperthyroidism in cats. Consistent application and veterinary monitoring are crucial for its effectiveness. Remember to consult your veterinarian for any concerns or changes in your pets condition.