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Maxitrol ( Neomycin Sulphate, Polymyxin, Dexamethasone)

Written by Dr. Feargus McConnell, BVSc on the Jan.16, 2024

Petdirect is dedicated to providing educational pet health content for pet parents. This article was written and reviewed by veterinary professionals to answer common questions about your pet’s medication. Our focus is on delivering unbiased information to help you understand how medication works, its potential side effects, and FAQs for your reference. Always administer medication directly as prescribed by your vet. This article shouldn’t take the place of advice from your vet.

What is Maxitrol®?

Maxitrol® is a prescription medication primarily used for treating bacterial eye infections. It is a human medication that may be prescribed off-label by a veterinarian for cats and dogs. It is available in an eyedrop or an ointment formula; however, both contain the following three active ingredients: Neomycin, Polymyxin B, and Dexamethasone.

How does it work?

The following ingredients combined offer both antibiotic and anti-inflammatory properties. Their specific functions are:

Polymyxin B Sulphate: An antibiotic effective against Gram-negative bacteria. It disrupts bacterial cell membrane permeability, causing bacterial death.

Neomycin Sulphate: A broad-spectrum antibiotic, effective against a range of bacteria.

Dexamethasone: This is a steroid that acts to reduce inflammation and pain associated with eye infections.

Dose and Administration

Preparation: Wash your hands thoroughly before handling the medication. Gently shake or mix the bottle if necessary (if it's eyedrops).

Restraining Your Pet: Calmly and securely hold your pet to prevent sudden movements. If necessary, another person may assist you by holding the pet.

Administering the Drops:

  • For Dogs and Cats: Tilt your pet's head back slightly. Using your free hand, gently pull down the lower eyelid to create a small pocket.
  • Squeeze the prescribed number of drops into the pocket, not directly on the eyeball, to avoid injuring the eye.
  • Release the eyelid and let your pet blink, spreading the medication over the eye's surface.

Administering the Ointment (if applicable):

  • Similar to drops, pull down the lower eyelid to create a pocket.
  • Squeeze a small amount of ointment (as prescribed) into the pocket. To avoid contamination or eye injury, do not let the tip of the ointment tube touch the eye or any surface.

After Administration: Gently close your pet's eye and hold it closed for a few seconds to help the medication distribute evenly. Praise your pet and offer a treat to create a positive association.

Contraindications and Precautions

Maxitrol should not be used in pets with a known sensitivity to its ingredients.

Do not use in cases of corneal ulcer.

Maxitrol® should not be combined with other medications such as non-steroidal anti-inflammatory drugs (NSAIDs). If your pet is already on medication, inform your veterinarian.

Potential Side Effects

While using Maxitrol®, some pets may experience side effects like:

  • Inflammation or increased pressure in the eye
  • Blurred vision or intolerance to light
  • Pupil dilation
  • Eyelid heaviness
  • Eye pain, swelling, itchiness, irritation, redness, and tearing

If you observe any of the following side effects, contact your veterinarian immediately.

Storage

Store Maxitrol® at room temperature, not exceeding 25°C. Do not refrigerate. Keep away from children and animals.

Frequently Asked Questions (FAQ)

Can Maxitrol® be used for both cats and dogs?

  • Yes, Maxitrol may be used in dogs and cats. However, its use is off-label and therefore it must be prescribed by a veterinarian.

What should I do if I notice side effects in my pet?

  • Contact your veterinarian immediately for advice.

Can Maxitrol® be used with other eye medications?

  • Seek advice from your veterinarian about any other medications your pet is currently taking to avoid potential interactions.

What is the shelf life of Maxitrol® after opening?

  • It should be discarded one month after first use.

Conclusion

While Maxitrol® can be an effective treatment for certain eye conditions in cats and dogs, it's crucial to use it under veterinary guidance. Always follow the prescribed instructions and monitor your pet's response to the medication. We hope this article provides a clear understanding of Maxitrol for your pet. Remember, always seek advice from your veterinarian for any health-related decisions for your pets.