Leventa® (Levothyroxine Sodium)

Leventa® contains Levothyroxine sodium as the active ingredient. It is used to treat hypothyroidism in dogs and Leventa® is typically prescribed to be given once a day to affected dogs. Canine hypothyroidism causes slowing of the dog’s metabolism due to thyroid hormone deficiency. Dogs with hypothyroidism are often lethargic, sleepy, and losing hair. Hypothyroid dogs often gain weight despite their diet remaining the same.

Levothyroxine is a synthetic form of thyroxine which is a naturally occurring thyroid hormone. This active ingredient works by replacing thyroxine, which is essential for maintaining metabolism and various physiological processes. Dogs with hypothyroidism have a thyroxine deficiency due to inadequate production by the thyroid gland. Administering Leventa® (Levothyroxine sodium) normalises thyroid hormone levels in the body.

Dosage varies based on the dog’s weight and other factors which should be determined by your veterinarian. Typically this medication can be given to dogs once daily, at the same time each day. The absorption of Leventa® is affected by food, so ideally give it 2-3 hours before food. Wear protective gloves when handling this product and thoroughly wash your hands after use.

Missed Dose:

If you miss a dose, consult with your veterinarian for guidance. Generally, you may be advised to administer it when remembered or skip the missed dose if it's nearly time for the next one. It is important to avoid double dosing.

Overdose:

For overdose concerns, immediately seek veterinary care or contact the New Zealand National Poisons Centre at www.poisons.co.nz/animal-helpline/ or 0800 869 738.

This product is contraindicated for use in dogs with hyperthyroidism or uncorrected adrenal insufficiency (hypoadrenocorticism).

While most pets tolerate this medication well, a small percentage may experience side effects such as:

• Weight loss
• Skin irritation
• Hyperactivity
• Increased heart rate
• Increased thirst and urination
• Vomiting
• Diarrhoea
• Increased thirst and respiratory rate

If these symptoms occur please contact your veterinarian immediately.

It is important to follow storage instructions as advised by your veterinarian. Store Leventa between 2°C and 8°C (refrigerate, DO NOT FREEZE). Keep sealed and away from food. Once open, use within 6 months. Keep out of reach of children and pets.

Regular monitoring of thyroid levels is recommended.

How long does it take for Leventa® to work?

• Leventa® may begin to show improvements within the first 1-2 weeks. Changes in weight, hair coat quality, and neurological signs can take 8-12 weeks to become noticeable. Regular veterinary visits are essential for ongoing evaluation and to ensure the treatment is working effectively.

What is the primary use of Leventa® in pets?

• It is used for thyroid hormone replacement therapy, primarily in dogs with hypothyroidism. Occasionally it is prescribed off-label for some cats after antithyroid treatment.

Is regular monitoring necessary?

• Yes, regular monitoring with your veterinarian of thyroid levels is important for adjusting doses and ensuring effective treatment.

What should I do in case of exposure or an overdose?

• Wear protective gloves when handling this product and thoroughly wash your hands after use. In case of exposure or an overdose contact your veterinarian or the New Zealand National Poisons Centre immediately.

Can other pets be affected by this medication?

• It is important to ensure other pets do not ingest the faeces of a pet on this medication, as it is excreted in faeces.