Itrazole (Itraconazole)

Itrazole is a medication used to treat fungal infections. It contains Itraconazole as the main ingredient. It is a human medication that may be prescribed off-label by a veterinarian for treating infections in pets like ringworm.

The main ingredient, Itraconazole interferes with the fungal cell membrane formation, inhibiting the growth and metabolism of the fungus.

The dosage of Itrazole varies depending on the type and severity of the infection. Capsules should be administered with food, enhancing absorption. Always handle the medication with care, washing hands and wearing gloves as necessary.

Overdose:

In case of a suspected overdose, immediately contact your veterinarian, seek emergency care, or reach out to the New Zealand National Poisons Centre (www.poisons.co.nz/animal-helpline/ or call 0800 869 738).

Liver Disease: Itraconazole is metabolized by the liver and can exacerbate existing liver conditions.

Kidney Disease: Similarly, animals with kidney issues may have difficulty processing this drug.

Heart Disease: Use caution in cases where the dog has heart failure.

Pregnancy: It should be avoided or used with caution in pregnant dogs, as it can cross the placenta and its effects on fetal development are not well understood.

Drug Interactions: Itraconazole can interact with other medications, potentially increasing their toxicity or reducing their efficacy. It's especially important to consider its use carefully if the dog is on other medications like anticoagulants, certain antibiotics, and drugs affecting the liver.

Itrazole is generally well-tolerated by pets. However, some may experience side effects such as:

• Loss of appetite
• Vomiting or diarrhoea
• Lethargy
• Weight loss
• Liver irritation

In rare cases, dogs may develop skin inflammation, ulcers, or leg swelling. If you notice any severe reactions or liver irritation symptoms (vomiting, loss of interest in food, yellowing of gums or eyes), contact your veterinarian immediately.

Store Itrazole capsules at controlled room temperatures. Always keep the medication in a tightly closed container, away from moisture and light, and out of reach of children and pets.

How long should a pet be prescribed Itrazole?

• The duration of Itrazole treatment varies. It can range from a few days to several months, depending on the infection's type, location, and severity. Your veterinarian will advise the appropriate length of treatment.

How quickly does Itrazole work in pets?

• Itrazole starts to act a few hours after ingestion. However, visible improvements in your pet’s condition might take a few days.

Can Itrazole be used for other animals?

• While Itraconazole is primarily prescribed for cats and dogs, veterinarians may use it off-label for other species. However, this article focuses only on its use in cats and dogs.

Are there any special instructions for administering Itrazole?

• Yes. Itraconazole capsules should be given with food. Proper hand hygiene and glove use are recommended when handling the medication.

What should I do if I miss a dose?

• If you miss a dose, consult with your veterinarian. They may advise you to administer it when you remember or wait for the next scheduled dose if it’s near, avoiding double dosing.