Written by Dr. Feargus McConnell, BVSc on the Jan.17, 2024
Petdirect is dedicated to providing educational pet health content for pet parents. This article was written and reviewed by veterinary professionals to answer common questions about your pet’s medication. Our focus is on delivering unbiased information to help you understand how medication works, its potential side effects, and FAQs for your reference. Always administer medication directly as prescribed by your vet. This article shouldn’t take the place of advice from your vet.
Incurin® (Estriol) is a medication used specifically for treating oestrogen-responsive urinary incontinence in spayed female dogs. It can be used to treat bitches with specific types of incontinence (leaking urine).
Incurin, containing the active ingredient estriol, a naturally occurring short-acting oestrogen, works by enhancing the muscle tone of the urethral sphincter. This improvement in muscle tone helps prevent urine leakage. Unlike longer-acting estrogens, estriol's short action duration is associated with a reduced risk of serious side effects.
The dosage of Incurin varies based on the individual response of each pet. It is not dosed by weight but rather tailored to the dog’s specific needs as determined by a veterinarian. Effective treatment is defined as no signs of incontinence for 7 days. Improvement is normally noticed after a few days of treatment. However, adjustment of the initial dose will often be necessary, so at least 7 days should be allowed before judging the full effect of a dose rate and the initial course should last at least 14 days. The medication can be given with or without food.
Missed dose:
If a dose is missed please advise with your veterinarian. However, it is usually suggested to be administered as soon as remembered, or skipped if it's nearly time for the next dose.
Overdose:
In case of overdose or side effects, immediately contact your veterinarian or the New Zealand National Poisons Centre at www.poisons.co.nz/animal-helpline/ or call 0800 869 738.
Do not use in male dogs or in intact bitches, as the efficacy has only been established in speyed bitches. Pets that are drinking and urinating more should not be treated with lncurin. lncurin is not recommended for use during pregnancy, lactation and in bitches younger than 1 year.
While Incurin is generally well-tolerated, some side effects may occur, including:
It's important to monitor your pet for these side effects and consult your veterinarian if they occur.
Incurin should be stored as advised via the storage label instructions. This usually involves storing at room temperatures avoiding any extreme temperatures. Tablets should be kept in their blister packs to protect them from moisture and light. Keep out of reach of children and pets.
Wash hands thoroughly after handling Incurin. Estriol presents a reproductive risk to humans, and pregnant or breastfeeding women should take extra care if handling Incurin. This group of people should wear gloves when handling Incurin and wash their hands thoroughly after handling.
How Quickly Does Incurin Work?
What is the duration of treatment for Incurin?
Is Incurin Safe for Dogs?
Incurin is a valuable medication for managing urinary incontinence in dogs. However, it's crucial to follow veterinary guidance regarding its use and monitor your pet for any adverse reactions. For any additional questions or concerns, consult your veterinarian.