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Hydrocortisone (Hydrocortisone)

Written by Dr. Feargus McConnell, BVSc on the Jan.16, 2024

Petdirect is dedicated to providing educational pet health content for pet parents. This article was written and reviewed by veterinary professionals to answer common questions about your pet’s medication. Our focus is on delivering unbiased information to help you understand how medication works, its potential side effects, and FAQs for your reference. Always administer medication directly as prescribed by your vet. This article shouldn’t take the place of advice from your vet.

What are Hydrocortisone Tablets?

Hydrocortisone tablets contain hydrocortisone aceponate as the active ingredient. Hydrocortisone can also be available in other forms, such as creams, shampoos or ointments. However the tablet form can be used for varying conditions to reduce inflammation such as managing allergies and skin disorders such as dermatitis. In addition, this medication is commonly prescribed to treat conditions such as Addisons’s disease (deficiency in adrenocortical hormones).

How does it work?

Hydrocortisone tablets, once ingested, are absorbed into the bloodstream, exerting a widespread effect on the body. They mimic natural corticosteroids from the pet's adrenal glands, crucial for managing inflammation and immune responses. The tablets primarily reduce inflammation, helping treat skin conditions. They also help modulate the immune system, beneficial in autoimmune diseases where the body's immune system is overactive. Lastly, in cases of adrenal insufficiency like Addison's disease, hydrocortisone serves as a hormone replacement, helping to maintain hormonal balance.

Dose and Administration

Always follow the directions on the label or as advised by your veterinarian. The tablet form of hydrocortisone is administered orally. Dose will vary depending on the condition that is being treated which will be determined by your veterinarian. However as a guide, once daily for Addison’s disease or twice daily for anti-inflammatory effects.

Missed Dose:

Generally, it's advised to administer the missed dose when remembered, unless it's close to the next scheduled dose. Avoid giving double doses.

Overdose:

Symptoms of overdose can include increased thirst or urination, vomiting or diarrhoea.

In case of suspected overdose, seek immediate veterinary care or contact the New Zealand National Poisons Centre at www.poisons.co.nz/animal-helpline/ or 0800 869 738.

Contraindications and Precautions

Hydrocortisone should be used in caution with pets with diabetes, infections, stomach ulcers, heart failure, kidney disease. It should not be given to pets currently being treated with NSAIDs. Inform your vet of all medications and supplements your pet is taking.

Potential Side Effects

As hydrocortisone belongs to the glucocorticoid class there are short term and long term side effects that could occur:

  • Increased appetite
  • Increased thirst and urination
  • Vomiting or diarrhoea
  • Excessive panting
  • Behavioural changes
  • Change in energy levels
  • Urinary tract infections
  • Muscle weakness
  • Liver enlargement
  • Cushing syndrome

Contact your vet if you observe any of the above side effects.

Storage

Hydrocortisone should be stored at a controlled room temperature and out of direct sunlight. Keep it tightly closed in its original container and out of reach of children and pets.

Monitoring

Pet’s receiving hydrocortisone long term should be closely monitored and regular vet visits may be required.

Frequently Asked Questions (FAQ)

Can I use human hydrocortisone based products on my dog or cat?  

  • Human hydrocortisone products are not recommended for pets. Consult your vet for pet-appropriate products.

Can hydrocortisone interact with other medications my pet is taking?

  • Hydrocortisone can interact with various other medications, which can either diminish its effectiveness or increase the risk of side effects. It's important to inform your veterinarian about all medications and supplements your pet is currently taking before starting hydrocortisone. Common interactions include nonsteroidal anti-inflammatory drugs (NSAIDs), certain diuretics, insulin, and some vaccines. Always consult with your vet before combining hydrocortisone with any other treatment to ensure it's safe for your pet.

How long does it typically take to see improvement in my pet's condition after starting hydrocortisone treatment?

  • The time it takes to see improvement in your pet's condition can vary depending on the specific condition being treated and the individual response of your pet. In some cases, improvements can be noticed within a few days, especially in conditions like allergic reactions or acute inflammation. However, for chronic conditions or more severe cases, it might take longer to observe noticeable changes. It's important to follow your veterinarian's guidance and not to stop or adjust the dosage without consulting them, even if you see improvements.

Conclusion

Hydrocortisone tablets can be an effective treatment for managing a wide range of health issues in pets. Hydrocortisone affects multiple body systems and therefore it is important to monitor your pet closely for side effects. We hope this article provides a clear understanding of hydrocortisone for your pet.