Written by Dr. Feargus McConnell, BVSc on the Jan.16, 2024
Petdirect is dedicated to providing educational pet health content for pet parents. This article was written and reviewed by veterinary professionals to answer common questions about your pet’s medication. Our focus is on delivering unbiased information to help you understand how medication works, its potential side effects, and FAQs for your reference. Always administer medication directly as prescribed by your vet. This article shouldn’t take the place of advice from your vet.
Cellcept contains Mycophenolate Mofetil and is an immune-suppressing drug used to treat various autoimmune conditions in dogs. These conditions may include immune-mediated hemolytic anaemia (IMHA), immune-mediated thrombocytopenia (ITP), glomerulonephritis, myasthenia gravis, meningoencephalitis, and pemphigus foliaceus. While it is commonly used in combination with other immunosuppressive medications, it can sometimes be prescribed as a sole treatment.
The Cellcept active ingredient, Mycophenolate mofetil turns into mycophenolic acid in the body. This acid blocks a specific enzyme, making it harder for the body to produce certain immune cells called lymphocytes. By doing this, it reduces the activity of the immune system, particularly the part that can cause auto-immune disease, by slowing down the growth of these immune cells and decreasing the production of antibodies.
This article focuses on the capsule form of this medication, however, there is a tablet and an oral suspension also available. In some cases, under direct veterinary supervision, it might be given by intravenous infusion, especially in a hospital setting. The specific dose and form will depend on the individual needs of the pet, as determined by a veterinarian.
Gloves should be worn when handling this medication and wash hands after giving the medication. Pregnant people or anyone trying to conceive should use extreme caution when handling this medication. Wear gloves, avoid inhaling dust from capsules or tablets and wash hands thoroughly.
Overdose:
In case of an overdose, contact your veterinarian immediately or National Poisons Centre (www.poisons.co.nz/animal-helpline/ or phone 0800 869 738) for more information. Overdose symptoms might include severe gastrointestinal upset leading to dehydration.
Cellcept should not be used in dogs with severe kidney disease or those who are hypersensitive to the medication. It is advised to use this medication with caution in pets with inflammatory bowel disease. This medication is not recommended in breeding, pregnant, or lactating pets.
It's important to discuss all medications and supplements your pet is taking with your veterinarian, as certain combinations can pose health risks.
Side effects in dogs may include gastrointestinal upset (diarrhoea, vomiting, loss of appetite), low energy (lethargy), decreased white blood cells (lymphopenia), growths related to the papillomavirus and skin infections. Intravenous use may lead to hypersensitivity reactions, and long-term use could increase the risk of internal infections and cancer. If you observe any of the above symptoms, contact your veterinarian immediately.
Store at controlled temperatures, in a tightly sealed container to protect it from moisture and light. It should be kept out of reach of children and pets.
Pregnant people or anyone trying to conceive should use extreme caution when handling this medication. Wear gloves and avoid inhaling dust from capsules or tablets and wash hands thoroughly.
What are the primary uses of Cellcept in dogs?
What should I do in case of an overdose?
Can Cellcept be used in all dogs?
Cellcept (Mycophenolate Mofetil) is a useful medication for treating various autoimmune conditions in dogs. However, it's crucial to follow your veterinarian's advice regarding its use. We hope this article provides a clear understanding of Cellcept for your pet. Remember, always seek advice from your veterinarian for any health-related decisions for your pets.