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Cartrophen (Pentosan)

Written by Dr. Feargus McConnell, BVSc on the Jan.16, 2024

Petdirect is dedicated to providing educational pet health content for pet parents. This article was written and reviewed by veterinary professionals to answer common questions about your pet’s medication. Our focus is on delivering unbiased information to help you understand how medication works, its potential side effects, and FAQs for your reference. Always administer medication directly as prescribed by your vet. This article shouldn’t take the place of advice from your vet.

What is Cartophen?

Pentosan Polysulfate Sodium, commonly referred to as PPS, is the primary active ingredient found in Cartrophen. It is used in the treatment of arthritis in dogs.

The ingredient PPS is known as a Disease Modifying Osteoarthritis Drug (DMOAD), which helps manage the symptoms and progression of joint diseases. Other conditions it can target can include:

  • Traumatic joint disease
  • Osteochondritis dissecans aka OCD (separation of cartilage and bone)
  • Synovitis (Inflammation of the Synovium)
  • Degenerative joint disease

How does it work?

Pentosan Polysulfate Sodium (PPS) possesses anti-inflammatory, anti-arthritic and chondroprotective activities. This medication is effective in treating multiple joints or joints that are difficult to pinpoint.

Cartrophen acts in several ways to alleviate joint problems, helping to reduce joint inflammation and improve mobility and quality of life.

Dose and Administration

Cartrophen is administered via intramuscular injection. The dose and frequency will be tailored to your pets needs by your veterinarian. However, the initial course typically consists of four injections a week apart, followed by weekly injections or injections every 4 weeks, depending on the pet's response and exercise intensity. Intra-articular injections are also possible, however your veterinarian will discuss what method is best for your pet.

Contraindications and Precautions

Reversible, localised discolouration and hair loss at the injection site can occur with long-term use.

Cartrophen is contraindicated in cases of clotting defects, traumatic haemorrhage, infection, liver/kidney failure, or within two days of surgery.

Potential Side Effects

Cartrophen is considered generally safe and well-tolerated by dogs. In rare cases, 15 minutes after the first injection a dog might vomit or be a little quieter than usual for up to 1-2 days. These transitory effects are rare and are only seen in a few dogs.

Storage

Store Cartrophen in a cool, dry place protected from direct sunlight. Discard the products 3 months after opening.

Frequently Asked Questions (FAQ)

Can Cartrophen be used for all pets?

  • Cartrophen is specifically used for dogs in treating various joint diseases. It's important to consult a veterinarian for appropriate use.

Are there any side effects of Cartrophen?

  • Possible side effects include reversible discolouration and hair loss at the injection site. It's crucial to follow the veterinarian's instructions regarding dosage and administration.

How long does it take to see improvement in my dog's condition after starting Cartrophen treatment?

  • The response time can vary depending on the individual dog and the severity of its joint condition. Some dogs may show improvement within a few weeks of starting treatment, while others may require a longer period to exhibit noticeable changes. It's important to follow the treatment plan as prescribed by your veterinarian and have regular check-ups to monitor your dog's progress. If your dog hasn’t improved after a month of treatment, or is getting worse, consult with your vet.

Conclusion

We hope this article provides a clear understanding of Cartophen for your pet. Remember, always seek advice from your veterinarian for any health-related decisions for your pets.