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Atopica (Cyclosporin)

Written by Dr. Feargus McConnell, BVSc on the Jan.16, 2024

Petdirect is dedicated to providing educational pet health content for pet parents. This article was written and reviewed by veterinary professionals to answer common questions about your pet’s medication. Our focus is on delivering unbiased information to help you understand how medication works, its potential side effects, and FAQs for your reference. Always administer medication directly as prescribed by your vet. This article shouldn’t take the place of advice from your vet.

What is Atopica?

Atopica capsules contain Cyclosporine as the active ingredient. It is often used to treat itchy skin in dogs when other causes of itching have been ruled out (atopic dermatitis). This offers a non-steroidal option to break the itch-lick-scratch cycle.

How does it work?

Atopica contains Cyclosporin, an immunosuppressive agent. It works by modulating the immune system. This action reduces the overactive immune response responsible for conditions such as dermatitis, thereby alleviating inflammation and itchiness symptoms. By targeting the immune system's response, Atopica effectively manages the symptoms and underlying causes of dermatological issues in dogs.

Dose and Administration

Follow as directed by your veterinarian, however the following is a typical guide for Atopica:

Administer as a once-daily dose for 30 days, at least one hour before or two hours after meals. After the initial loading phase, the dose can often be tapered down to every-other day or twice weekly. The goal is to find the minimum frequency of dosing that effectively controls the itch.

Missed Dose:

If you miss a dose, administer it as soon as possible. However, if it's close to the next scheduled dose, skip the missed one. Do not double up on doses.

Overdose:

The following symptoms can be seen in cases of overdose:

  • Loss of appetite
  • Vomiting
  • Diarrhoea
  • Increased thirst
  • Increase urination
  • Jaundice
  • Lethargy

If these symptoms are observed, contact your emergency veterinarian immediately or contact the New Zealand National Poisons Centre (www.poisons.co.nz/animal-helpline/ or 0800 869 738).

Contraindications and Precautions

Atopica is contraindicated in dogs with a history of cancer. It's crucial to consult with your veterinarian to determine if Atopica is suitable for your pet. It should not be given to very young dogs, pregnant or lactating bitches.

Potential Side Effects

Although generally well tolerated, the more common side effects can include gastrointestinal issues like vomiting and diarrhoea. Less common side effects can include swollen gums, ear infections, urinary tract infections, lethargy, and seizures. In very rare cases, it can affect blood sugar levels and should be used cautiously in dogs with diabetes mellitus or kidney issues.

Storage

Capsules (Dogs): Store at room temperature, away from moisture and light. Keep the container tightly closed.

Frequently Asked Questions (FAQ)

Can I give the Oral solution to my dog and the tablet version to my cat?

  • Follow as prescribed by your veterinarian, however typically the Atopica Oral solution is prescribed for cats and the Atopica tablets are prescribed for dogs.

Can Atopica interact with other medications my pet is taking?

  • When giving Cyclosporin to your pet, be cautious if they are also on medications that are metabolised in a similar way, as this can alter Cyclosporin’s blood levels. This can include common drugs like antifungals, antibiotics, and gastrointestinal medications. Always inform your veterinarian about every medication your pet is taking to avoid potential interactions and ensure safe treatment.

Conclusion

We hope this article provides a clear understanding of Atopica for your pet. Remember, always seek advice from your veterinarian for any health-related decisions for your pets.