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Arthropen (Pentosan Polysulfate Sodium)

Written by Dr. Feargus McConnell, BVSc on the Jan.16, 2024

Petdirect is dedicated to providing educational pet health content for pet parents. This article was written and reviewed by veterinary professionals to answer common questions about your pet’s medication. Our focus is on delivering unbiased information to help you understand how medication works, its potential side effects, and FAQs for your reference. Always administer medication directly as prescribed by your vet. This article shouldn’t take the place of advice from your vet.

What is Arthropen?

Arthropen injection contains Pentosan Polysulfate Sodium, commonly referred to as PPS, as the primary active ingredient. This ingredient is a semi-synthetic polysaccharide which is used in the treatment and prevention of non-infectious inflammatory joint diseases in dogs. It is also licensed for use in horses.

The ingredient PPS is known as a Disease Modifying Osteoarthritis Drug (DMOAD), which helps manage the symptoms and progression of joint diseases, such as arthritis.

How does it work?

Pentosan Polysulfate Sodium (PPS) possesses anti-inflammatory, anti-arthritic and chondroprotective activities. This medication is effective in treating multiple joints or joints that are difficult to pinpoint. Arthropen acts in several ways to alleviate joint problems, reduce inflammation and discomfort associated with arthritis.

Dose and Administration

Arthropen is administered by injection. The dose and frequency will be tailored to your pets needs by your veterinarian. However, the initial course typically consists of four injections a week apart, followed by weekly injections or injections every 3-4 weeks, depending on the pet's response and exercise intensity.

Contraindications and Precautions

Arthropen is contraindicated in cases of clotting defects, traumatic haemorrhage, infection, liver and kidney failure, or within two days of surgery.

Potential Side Effects

Swelling at the injection site. Reversible, localised discolouration and hair loss at the injection site may occur.

Storage

Store Arthropen in a cool, dry place protected from direct sunlight.

Frequently Asked Questions (FAQ)

Can Arthropen be used for all pets?

  • Arthorpen is specifically used for dogs in treating various joint diseases. It is also licensed for use in horses.

Are there any side effects of Arthropen?

  • Possible side effects include reversible discolouration and hair loss at the injection site.

How long does it take to see improvement in my dog's condition after starting Arthropen treatment?

  • The response time can vary depending on the individual dog and the severity of its arthritis or joint issues. Some dogs may show improvement within a few weeks of starting treatment, while others may require a longer period to exhibit noticeable changes. If your dog doesn’t show noticeable improvement after one month of treatment, or is getting worse, consult with your vet.

Conclusion

We hope this article provides a clear understanding of Arthropen for your pet. Remember, always seek advice from your veterinarian for any health-related decisions for your pets.