Sileo Gel (Dexmedetomidine)

Active Ingredient:

Each syringe contains 3ml of 0.1mg/ml Dexmedetomidine

Additional Information:

Understanding Sileo Oromucosal Gel for Dogs

Sileo® is an oromucosal gel for dogs designed to alleviate acute anxiety and fear associated with noise. It contains the active ingredient dexmedetomidine hydrochloride, a well-known alpha-2 adrenoceptor agonist used for its sedative and anxiolytic effects.

What Causes Noise-Related Anxiety in Dogs?

Noise-related anxiety in dogs can be triggered by fireworks, thunderstorms, and other loud noises. The fear response can include panting, trembling, hiding, and other stress-related behaviours. Sileo works by mimicking the calming effects of alpha-2 adrenoceptor stimulation in the brain.

Signs and Symptoms of Noise-Related Anxiety

Dogs affected by noise-related anxiety may exhibit signs such as panting, shaking, seeking comfort from their owners, hiding, attempting to escape, and in some cases, inappropriate weeing and pooing, or destructive behaviour.

How is Noise-Related Anxiety Treated?

Sileo gel is administered between the dog’s cheek and gum, allowing for rapid absorption and quick onset of action. It should be used as directed by a veterinarian and is intended for oromucosal use only, not for ingestion.

Monitoring and Care at Home

After administering Sileo, monitor your dog for any signs of excessive sedation or adverse reactions. Keep your dog in a comfortable, warm place, and avoid offering food or water until the medication's effects have worn off.

Prognosis

When used as directed, Sileo is effective in managing noise-related anxiety and fear in dogs, allowing them to remain calm during stressful situations. The prognosis for dogs treated with Sileo for noise aversion is generally very good.

Preventative Care

To prevent noise-related anxiety, plan ahead by identifying potential noise triggers and administer Sileo 30-60 minutes before the expected noise event. Ensure your dog is in a safe, secure place where they feel comfortable.

FAQs Section

How quickly does Sileo work?

Sileo typically starts to work within 30 to 60 minutes after administration.

Can Sileo be used for all dogs?

Sileo should not be used in dogs with severe cardiovascular, respiratory, liver, or kidney disease, or conditions of shock or extreme stress. It is also not recommended for dogs under 6 weeks of age or with known hypersensitivity to dexmedetomidine.

How often can Sileo be administered?

If the noise continues and your dog's anxiety returns, additional doses may be given at intervals of 2 hours, with a maximum of 5 doses per event.

What should I do if my dog swallows the gel?

If the gel is swallowed, it may not be effective. Do not administer another dose for at least two hours.

Are there any side effects?

Possible side effects include vomiting, diarrhoea, sedation, a slower heart rate, a slower respiratory rate, and pale gums. Contact your veterinarian if any concerning symptoms arise.